William McGregor Paxton (1869–1941) was an American painter and instructor born in Baltimore and active in Boston. He received his training at Cowles Art School and the Museum of Fine Arts School in Boston, where he also taught. Paxton embraced the Boston School paradigm and co-founded The Guild of Boston Artists.
Paxton specialized in portraits and interior scenes featuring women, often including his wife, Elizabeth Okie Paxton. His portrait subjects included presidents Grover Cleveland and Calvin Coolidge. He typically worked from live models, bringing academic French painting influences to his figurative works and creating Vermeer-influenced interiors with upper-class female figures.
His works are held in numerous museums across the United States.