Léon François Comerre (1850–1916) was a French academic painter and sculptor. Born in Trélon, he died in Paris. He undertook studies in Lille and Paris, later working in both London and Paris. Comerre won the prestigious Prix de Rome in 1875. His work is often associated with academic art and Symbolism.
Comerre specialized in portraits, particularly of women, and explored Orientalist themes. His oeuvre also included historical and mythological scenes, as well as nudes. An example of his portraiture is Madame Léon Clapisson (1883).
He exhibited his works successfully in the Salon. Comerre was married to the painter Jacqueline Comerre-Paton and was the uncle of artist Albert Gleizes.